Objective type Question from Developmental Biology | Ch. Fertilization and Zygote Formation

 

1. The process that enables spermatozoa to move along the female reproductive tract and prepares for fertilization is called

a. Acrosomal reaction

b. Maturation

c. Capacitation

d. Flagellation

 

2. The time taken for the capacitation process that precedes fertilization in humans is

a. 1-2 hours

b. 2-4 hours

c. 5-6 hours

d. 10 hours

 

3. Capacitation of the sperm induces changes in the metabolism of

a. Lipids

b. Glycoprotein

c. Both (a) and (b)

d. Neither (a) not (b)

 

4. Capacitation of the sperm increases

a. Metabolism

b. Motility

c. Both (a) and (b)

d. Neither (a) not (b)

 

5. The layer on the egg that acts as a cross species fertilization barrier is

a. Zona pellucida

b. Follicle cells

c. Plasma membrane

d. Egg coat

6. The number of glycoprotein types that constitute the mammalian zona pellucida is

a. 1

b. 2

c. 3

d. 4

 

7. The three glycoprotein types that constitute the mammalian zona pellucida are

a. ZP1, ZP2 and ZP3

b. ZP2, ZP3 and ZP5

c. ZP5, ZP6 and ZP8

d. ZPa, ZPb and ZPc

8. The glycoprotein type of the mammalian zona pellucida that acts as a sperm receptor is

a. ZP1

b. ZP2

c. ZP3

d. ZPa

 

9. The event that follows the binding of sperm to the ZP3 in the zona pellucid is

a. Fertilization

b. Clevage

c. Capacitation

d. Acrosomal reaction

 

10. The acrosoma contents are released by

a. Lysis

b. Vesicular transport

c. Receptor mediated Transcytosis

d. Exocytosis

 

11. The acrosomal reaction releases

a. Proteases

b. Hyaluronidase

c. Both (a) and (b)

d. Neither (a) nor (b)

 

12. Prevention of fertilization by more than one sperm usually is due to

a. Cortical reaction

b. Zona pellucida

c. Capacitation

d. Acrosomal reaction

 

13. The primary block to polyspermy in eggs is by

a. Rapid depolarization of the plasma membrane

b. Rapid polarization of the plasma membrane

c. Rapid permeability of the plasma membrane

d. Rapid repolarization of the plasma membrane

 

14. The secondary block to polyspermy in eggs is by

a. Rapid depolarization of the plasma membrane

b. Rapid polarization of the plasma membrane

c. Cortical reaction

d. Acrosomal reaction

 

15. Fusion of sperm to the egg plasma membrane triggers the

a. Gated ion channel signaling pathway

b. Receptor mediated endocytic signaling pathway

c. Inositol phospholipid cell signaling pathway

d. The G protein signaling pathway

 

16. The cortical reaction in the egg is mediated by the raise in the levels of

a. Ca2+

b. Mn2+

c. K+

d. Cl2+

 

17. The haploid nuclei in the just fertilized egg are called

a. Prenuclei

b. Pronuclei

c. Nucleoids

d. Immature nuclei

 

18. Apart from the DNA, one other important component contributed by the sperm to the fertilized egg is

a. Centrosome

b. Centriole

c. Mitochondria

d. Plasma membrane

 

19. Fusion of gamete pronuclei is known as

a. Fertilization

b. Hybridization

c. Amphimixis

d. Amplexus

 

20. The life span of human egg is

a. 4 hours

b. 8 hours

c. 12 hours

d. 24 hours

 

21. The life span of human sperm is

a. 4 hours

b. 8 hours

c. 12 hours

d. 24 hours

 

22. The pores on the membranes surrounding eggs that are useful for the entry of sperm are known as

a. Microphyles

b. Pseudophyles

c. Gap junctions

d. Ion channels

 

23. The cementing substance of the corona radiata of an egg that binds follicular cells is

a. Hyaluronidase

b. Zylase

c. Hyaluronic acid

d. Fertilizin

 

24. The enzyme contained in the sperm acrosomal granules that help in penetration through the corona radiata of an egg is

a. Hyaluronidase

b. Antifertilizin

c. Hyaluronic acid

d. Fertilizin

 

25. The activation of ovum is triggered by

a. Folliculation

b. Sperm reaching the corona radiata

c. Sperm reaching the egg plasma membrane

d. Fertilization

26. The layer covering the early blastula that hold the blastomeres together is called

a. Vitelline layer

b. Hyaline layer

c. Cortical layer

d. Epidermis

 

27. The liquid in the cortical granules is called

a. Vitelline fluid

b. Perivitelline fluid

c. Cortical fluid

d. Hyaluronidase

 

28. The series of reactions that occur in the sperm upon contacting an egg are called

a. Acrosomal reactions

b. Fertilization

c. Amphimixis

d. Cortical reactions

 

29. The series of reactions that occur in the egg upon contact with a sperm are called

a. Acrosomal reactions

b. Ertilization

c. Amphimixis

d. Cortical reactions

30. The chemical substances produced by the gametes that are useful for fertilization are collectively called

a. Gynogamones

b. Androgamone

c. Gamones

d. Fertilizins

ANSWERS TO MCQs

1. c 2. c 3. c 4. c 5. a 6. d 7. a 8. c 9. d 10. d

11. c 12. a 13. a 14. c 15. c 16. a 17. b 18. b 19. c 20. d

21. d 22. a 23. c 24. a 25. c 26. b 27. b 28. a 29. d 30. c