1. The cell cycle is the period between two
a. S stages
b. G1 and M stage
c. S and M stage
d. M stages
2. The stages of interphase can include
a. G1, S, G2, M
b. G0, G1, G2, M
c. G0, S, G2, M
d. G0, G1, G2, S, M
3. Non-dividing cells are said to be
a. Apoptotic
b. Necrotic
c. Quiescent
d. Senescence
4. Healthy cells that cannot re-enter the cell cycle are
a. Differentiated
b. Terminally differentiated
c. Apoptotic
d. Necrotic
5. The Nobel prize for work done on cell cycle promoting
molecules was awarded to
a. Paul Nurse, Tim Hunt, and Leland Hartwell
b. Thomas Morgan, Tim Hunt, Leland Hartwell
c. Paul Nurse, Thomas Morgan, and Leland Hartwell
d. Paul Nurse, Tim Hunt, and Thomas Morgan
6. The Mitosis promoting factor (MPF) comprises of
a. Cyclin-dependent kinase 1(Cdk1)
b. Cyclin B
c. Both (a) and (b)
d. None of the above
7. The stage of cell cycle when cellular organelle
synthesis occurs is
a. G1
b. S
c. G2
d. M
8. The stage of cell cycle when checking for errors in
DNA occurs is
a. G1
b. S
c. G2
d. M
9. The structural maintenance of chromosomes (SMC)
proteins do not include
a. Condensin I
b. Condensin II
c. Cohesins
d. Troponin
10. The mitotic promoting factors (MPFs) constitute
a. Cyclin B and CdK1
b. Cyclin A and CdK4
c. Condensin and CdK2
d. Cohesins and CdK4
11. A protein member of inhibitors of apoptosis that
present in the G2 - M phase and not in the interphase stage is
a. Condensins
b. Cohesins
c. Survivins
d. Cyclins
12. The chromosome segregation checkpoint occurs at the
end of the cell cycle phase
a. M
b. G1
c. S
d. G2
13. The number of main DNA damage checkpoints in a cell
cycle is
a. 1
b. 2
c. 3
d. 4
14. The unreplicated DNA checkpoint occurs at the end of
the cell cycle phase
a. M
b. G1
c. S
d. G2
15. Examples of mitogens are
a. Phytohemeagglutinin and Concanavalin A
b. Phytohemeagglutinin and agarose
c. Interleukin-7 and CD28
d. cKit and Ikaros
16. The mid-G1 cyclin dependent kinase (CDK) is
a. Cln3
b. Cdc28
c. Cln1
d. Cln2
17. The late-G1 cyclin dependent kinases (CDK) are
a. Cln3 and Clb4
b. Cdc28 and CDK1
c. Cln1 and Cln2
d. Cln2 and Cln3
18. The early S phase cyclin dependent kinases (CDK) are
a. Clb5 and Clb6
b. Cdc28 and CDK1
c. Cln1 and Cln2
d. Clb2 and Clb3
19. The late S phase cyclin dependent kinases (CDK) are
a. Clb5 and Clb6
b. Clb3 and Clb4
c. Cln1 and Cln2
d. Clb2 and Clb3
20. The late M phase cyclin dependent kinases (CDK) are
a. Clb5 and Clb6
b. Clb3 and Clb4
c. Clb1 and Clb2
d. Clb2 and Clb3
21. The cyclin corresponding to cyclin dependent kinase
Cyclin B is
a. Mitotic cyclin
b. S-phase cyclin
c. Mid G1 cyclin
d. Late G1 cyclin
22. The cyclin corresponding to cyclin dependent kinase
Cyclin A is
a. G2 cyclin
b. S-phase and mitotic cyclin
c. Mid G1 cyclin
d. Late G1 cyclin
23. The cyclin corresponding to cyclin dependent kinase
Cyclin E is
a. G1 and G2 cyclin
b. S-phase and mitotic cyclin
c. Mid G1 cyclin and late G1 cyclin
d. Late G1 and S phase cyclin
24. Cells in culture can be arrested at the G0 stage by
a. Methotextrate
b. Colchicine
c. Phytohemeagglutinin
d. Serum starvation
25. Cells in culture can be arrested at the M stage by
a. Methotextrate
b. Colchicine
c. Phytohemeagglutinin
d. Serum starvation
ANSWERS:
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1. d 2. d 3. c 4. b 5. a 6. c 7. a 8. c 9. d 10. a |
11. c 12. a 13. c 14. d 15. a 16. a 17. c 18. a 19. b 20. c |
21. a 22. b 23. d 24. d 25. b |
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